Prevalence of liver fibrosis and steatotic liver disease in community-dwelling adults in China (the CHESS-LiverHealth project): cross-sectional baseline data from a prospective cohort study.

Liver fibrosis and steatotic liver disease affect over 4% and 43% of community-dwelling adults in China, with higher prevalence linked to metabolic and alcohol factors.

• Why it matters: Understanding the true burden of chronic liver disease in China is crucial due to its rapid increase driven by obesity, diabetes, and alcohol use, yet community-based data are scarce.
• What they did: The study analyzed baseline data from 25,736 adults across China using vibration-controlled transient elastography to assess liver stiffness and steatosis, and identified associated risk factors.
• The result: Findings reveal significant prevalence of liver disease associated with metabolic conditions and alcohol consumption, highlighting the need for community screening and early intervention strategies.