A One Health perspective on mobile genetic elements and associated antibiotic resistance genes in non-human A. baumannii.

Mobile genetic elements in non-human A. baumannii populations harbor resistance genes and suggest circulation between human and non-human environments.

• Why it matters: Understanding the spread of antimicrobial resistance across different ecosystems is crucial for controlling public health threats, yet non-hospital reservoirs are underexplored.
• What they did: The review examines insertion sequences, transposons, and plasmids in non-human A. baumannii from animals, food, and environments, highlighting their role in resistance gene dissemination.
• The result: Findings indicate non-human populations act as reservoirs and vectors for resistance genes, emphasizing the importance of a One Health approach to monitor and mitigate antimicrobial resistance spread.