The abstract is read at the publisher; the summary is JClub's.
In 723 adults, diffusion-based structure–function coupling is strongest during movie-watching, intermediate at rest, and weakest during working memory, dropping further with higher working-memory load.
- Why it matters: It remains unclear whether anatomical constraints on functional organization are constant or instead shift with cognitive state, and whether rest best reveals structure–function relationships.
- What they did: Using diffusion MRI and fMRI in two independent adult cohorts, the study quantified structure–function coupling across movie-watching, rest, and working-memory tasks, including a load manipulation in the primary cohort.
- The result: The movie–rest coupling difference replicated in the independent sample, and state effects overlaid a stable unimodal-to-transmodal hierarchy, with movie-watching preferentially enhancing coupling in sensory and language systems.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.