The abstract is read at the publisher; the summary is JClub's.
Routine galantamine reversal after sevoflurane-based ENT surgery in 207 children aged 2–17 is linked to 0/102 cases with PAED > 10 versus 19/105 without prophylaxis.
- Why it matters: Emergence delirium is common in children after general anesthesia, with preschool age and ENT procedures as risk factors, and a cholinergic deficiency rationale motivates testing galantamine.
- What they did: In a retrospective observational study (Oct 2025–Jan 2026), two anesthesiologists’ practices created prophylactic galantamine reversal (n=102) versus no routine reversal (n=105), with PAED assessed after extubation.
- The result: Therapeutic galantamine for impaired emergence was followed by delirium resolution with restoration of meaningful interaction without sedatives, supporting further study of prophylactic versus therapeutic use.
The findingWhy it mattersWhat they didThe result
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