The abstract is read at the publisher; the summary is JClub's.
A chromosome-scale genome assembly and multi-omic atlas for the common bent-wing bat Miniopterus schreibersii integrates lncRNA, EVE mapping, and same-individual RNA editomics to enable immune-regulation studies.
- Why it matters: Bats host many viruses yet often show limited clinical disease, implying distinctive immune regulation and tolerance; the roles of non-coding RNAs and RNA editing are still underexplored.
- What they did: The work builds a contiguous chromosome-scale genome assembly and pairs it with multi-tissue transcriptomics, lncRNA identification with synteny analysis, endogenous viral element mapping, and RNA editomic profiling from the same individuals.
- The result: The resulting resource supports investigations of genome organization, transcriptional regulation, evolutionary relationships, and post-transcriptional modifications linked to bat viral interactions and immune regulation.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.