The abstract is read at the publisher; the summary is JClub's.
In a single-center Zurich cohort of 219 adults with confirmed cerebral venous thrombosis, adjusting for age and body-mass index removed women’s excess headache and cortical vein involvement.
- Why it matters: Reported sex differences in presentation may reflect baseline differences in age and body-mass index rather than sex itself, leaving uncertainty about what truly explains symptom and imaging patterns.
- What they did: Women and men were compared across presentation, imaging, and laboratory data, then each sex difference was re-estimated at equal age and body-mass index; secondary analyses assessed outcomes in those with follow-up.
- The result: After adjustment, headache (OR 1.17 [95% CI, 0.54-2.54]) and cortical vein thrombosis (OR 2.05 [95% CI, 0.59-7.06]) were no longer linked to sex, while higher platelet counts (+56 x 109/L [95% CI, 26-86]) and elevated acute-phase markers without infection (OR 2.91 [95% CI, 1.44-5.87]) persisted; among assessed patients, functional independence and other outcomes did not differ by sex.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.