The abstract is read at the publisher; the summary is JClub's.
Lower household income (<$25,000 vs $200,000 or more) is linked to higher all-cause mortality and worse kidney outcomes in 218,098 All of Us participants.
- Why it matters: It is unclear whether socioeconomic gaps are larger for progression of kidney function than for first recorded CKD diagnosis, and how these relate to mortality across baseline kidney states.
- What they did: In a retrospective cohort from the All of Us Research Program (follow-up to January 1, 2025), adjusted hazard ratios were estimated for mortality and kidney outcomes, including sustained 40% eGFR decline and incident CKD events.
- The result: Income below $25,000 showed higher adjusted hazard ratios for mortality (2.68), sustained decline (3.57), incident CKD diagnosis (2.13), incident G3a-or-worse (2.15), and kidney failure (3.08), with inequality effects about twice as large for decline and failure than for recorded diagnosis.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.