The abstract is read at the publisher; the summary is JClub's.
Greater scam susceptibility in 116 older adults without dementia is linked to higher neurite density index and lower orientation dispersion index in the middle temporal gyrus.
- Why it matters: Financial exploitation risk is common, and prior work suggests brain microstructure may relate to vulnerability, but diffusion tensor imaging cannot separate tissue properties.
- What they did: Using 7-Tesla NODDI, researchers quantified neurite density index, orientation dispersion index, and free-water fraction in seven early-Alzheimer’s-related regions, then ran multivariate regressions with covariate adjustment and pFDR correction.
- The result: In the middle temporal gyrus, NDI showed beta=0.30 (pFDR=.025) and ODI showed beta=-0.28 (pFDR=.044), and these MTG metrics explained additional variance beyond cortical thickness and other macrostructure measures.
The findingWhy it mattersWhat they didThe result
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