The abstract is read at the publisher; the summary is JClub's.
In Ghana’s 2021–2022 yellow fever outbreaks, raising baseline vaccination coverage to 80% is estimated to avert 20 additional severe cases (95% UI 14–25).
- Why it matters: Even with an effective yellow fever vaccine, outbreaks have continued, and it is unclear how EYE strategy changes in coverage and response timing affect morbidity and mortality since 2017.
- What they did: Mathematical models were calibrated to Ghana (2021–2022) and South Sudan (2023–2024) outbreaks, then used to project severe-case morbidity under different vaccination coverage and response-time thresholds.
- The result: In South Sudan (2023–2024), shortening reactive vaccination response from 61 to 20 days and increasing baseline coverage to 80% avert 80 (95% UI 68–91) and 95 (95% UI 80–112) severe cases, respectively, or 103 (95% UI 85–120) when combined.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.