The abstract is read at the publisher; the summary is JClub's.
In a cellular-scale discrete model of the actomyosin cortex, heterogeneous local cortical tension emerges and persists despite continuous turnover, with tensile energy per element correlating most strongly for actin filaments.
- Why it matters: It remains unclear how dynamic steady states—where components are replaced and contractility is spatially biased—maintain tension-bearing structures and reorganize them through flow.
- What they did: They built a discrete-element cortex model of actin filaments, cross-linkers, and myosin minifilaments, reconstructed surface stress from internal forces, and compared AF disassembly, relocation, and myosin-localization mechanisms.
- The result: Highly stretched AFs preferentially appear in high-tension regions and align with the first-principal-tension orientation; global AF-network connectivity and cell-scale cortical tension are maintained, with tension-pattern reorganization linked to myosin persistence time.
The findingWhy it mattersWhat they didThe result
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