The abstract is read at the publisher; the summary is JClub's.
Maternal diagnosis after 28 weeks, absence of prenatal care versus eight or more visits, and reinfection during pregnancy are strongly linked to congenital syphilis in 743 mother–infant pairs in Bogota, Colombia (2017–2024).
- Why it matters: Congenital syphilis remains preventable yet incidence in Colombia stays above elimination targets, and locally actionable care gaps are unclear for socially vulnerable patients in Bogota.
- What they did: Using retrospective surveillance and clinical records from Subred Integrada de Servicios de Salud Sur E.S.E., the study compared 285 congenital syphilis cases with 458 controls and fit multivariable logistic regression with backward elimination.
- The result: Late diagnosis (aOR 17.75; 95% CI 11.81–26.69), no prenatal care (aOR 12.74; 5.03–32.25), and reinfection (aOR 3.02; 1.73–5.29) remained independently associated, while documented syphilis history showed lower odds (aOR 0.45; 0.25–0.82); discrimination was high (AUC 0.860).
The findingWhy it mattersWhat they didThe result
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