The abstract is read at the publisher; the summary is JClub's.
In northern Kenya sentinel surveillance, 13.4% of malaria infections carried the SP quintuple mutant haplotype IRNI/GEAA, while resistance-associated mutations were higher after recent SMC.
- Why it matters: Program effectiveness in pastoralist settings is threatened by delivery and uptake gaps and by parasite resistance to SPAQ, requiring real-time surveillance to target interventions.
- What they did: At selected health facilities, every malaria case among SMC-eligible children was investigated for missed cycles and timing, and parasite alleles linked to SP and AQ resistance were genotyped and related to SMC uptake.
- The result: Household travel was a more common reason for missing SMC than caregiver refusal; over one-third missed the most recent cycle and 15% were near the next scheduled dose, and sentinel findings enabled targeted distribution and sensitization.
The findingWhy it mattersWhat they didThe result
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