The abstract is read at the publisher; the summary is JClub's.
Peri-urban adults in Sekondi-Takoradi, Western Region, Ghana show 75.7% mpox vaccine acceptance, with perceived vaccine safety strongly linked to lower hesitancy and refusal.
- Why it matters: No prior Ghana study had used a theory-based framework to identify drivers of mpox vaccine acceptance before the October 2025 sub-national campaign in this region.
- What they did: In a community cross-sectional survey of 580 adults (July–August 2025) across six peri-urban areas, acceptance (accept/hesitant/refuse) was analyzed with chi-square tests and multinomial logistic regression adjusting for sociodemographics and Health Belief Model constructs.
- The result: Those viewing the vaccine as very safe had much lower adjusted odds of hesitancy (adjusted odds ratio 0.02, 95% CI 0.00–0.12) and refusal (0.03, 0.01–0.13); uncertainty about effectiveness predicted hesitancy (9.83, 1.95–49.50), and education and area differences were observed.
The findingWhy it mattersWhat they didThe result
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