The abstract is read at the publisher; the summary is JClub's.
In a retrospective cohort of 5,248 IMSS primary-care COVID-19 cases in León, Mexico, presenting after 3 days from symptom onset was linked to higher death risk (6.0% overall).
- Why it matters: Time to first care is a potentially modifiable factor for COVID-19 outcomes, yet it is seldom quantified in primary care settings with universal insurance coverage.
- What they did: They analyzed SINOLAVE surveillance records for April 2020–April 2021, using wave comparisons and multivariable logistic regression, including sensitivity analyses adjusting for severity signs at first contact.
- The result: Case fatality was 3.0% within 3 days versus 9.1% later, and delayed presentation (>3 days) showed an adjusted odds ratio of 1.98, which attenuated to 1.20 after severity adjustment.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.