A Retrospective Real-World Assessment of Motor Status After Stroke Using a Home-Based Brain-Computer Interface

In 452 US adults with chronic stroke prescribed at-home IpsiHand BCI, Upper Extremity Fugl-Meyer scores improved by week 12 (mean +4.3 points) and continued rising to week 52 (+8.1).

• Why it matters: Upper extremity deficits after stroke often persist, and it is unclear whether BCI benefits seen in trials translate to routine at-home care, especially for severe chronic impairment.
• What they did: This retrospective observational study followed regular users (average >1 session/week) with video-administered UEFM every 4 weeks, modeling change to week 52 using mixed models and multiple imputation.
• The result: By week 12, 31.7% reached the 5.25-point MCID, and mean change reached MCID by week 16 (5.6); improvements persisted through 1 year, supporting further randomized evaluation beyond 12 weeks.

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