EIT-based non-invasive measurements correlate with pulmonary arterial pressure in patients

In seven patients with cardiovascular disease, EIT timing markers across heart and lung regions correlate with invasively measured mean pulmonary artery pressure, with mean absolute Spearman coefficients of 0.74 across 56 combinations.

• Why it matters: Clinicians need non-invasive ways to estimate pulmonary haemodynamics, but the link between cardiac-synchronized EIT timing and invasively measured mPAP in patients is not established.
• What they did: During routine surgery in an apnoea phase, ECG, EIT, and mPAP were recorded while phenylephrine induced pressure changes; four waveform timing definitions produced eight ECG R-wave delay markers.
• The result: At least one timing marker per patient had an absolute Spearman value above 0.79, and the lung second-derivative timing marker exceeded 0.90 in four patients, suggesting EIT timing may predict mPAP.

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