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Chlamydia trachomatis and Neisseria gonorrhoeae in newborns with and without neonatal conjunctivitis: cross-sectional study in Papua New Guinea
medRxiv · · Preprint · Open access
Low, Mengi + 12 more
Abstract ↗AI summary
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Chlamydia trachomatis and Neisseria gonorrhoeae were detected in newborns without conjunctivitis in Papua New Guinea, with 6.6% overall prevalence and 87.0% asymptomatic.
- Why it matters: Mother-to-child transmission during vaginal birth can cause neonatal conjunctivitis, but the frequency and asymptomatic burden in babies without eye symptoms are poorly quantified.
- What they did: In a cross-sectional study nested in a randomized controlled trial in Papua New Guinea, conjunctival swabs were collected at 1–2 weeks after birth and tested by PCR for both pathogens.
- The result: Among babies with results, C. trachomatis was found in 12/97 (12.4%) with conjunctivitis versus 7/211 (3.3%) without, while N. gonorrhoeae was 1/97 (1.0%) versus 6/210 (2.9%); overall, 87.0% of detected infections were asymptomatic.
The findingWhy it mattersWhat they didThe result
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