Dosimetric Characterization and Workflow Optimization of the FLASH-SARRP for Reliable Preclinical Radiobiological Studies

Simultaneous irradiation on the FLASH-SARRP achieves ~80 Gy/s in a homogeneous field, but tube synchronization shows a 10 ms average delay that creates temporal dose-rate heterogeneity.

• Why it matters: Preclinical FLASH experiments need reproducible ultra-high dose-rate delivery, yet integrated dose checks can miss timing mismatches between dual tubes.
• What they did: The beam was characterized with Gafchromic films for spatial dose and a plastic scintillating fiber for real-time temporal monitoring, including 3D-printed spacers and cross-calibration plus fiber pre-irradiation verification.
• The result: Inter-session variability was ~11% with low intra-session variability (~4%), and the QA workflow reduced inter-session variability to ~5%, enabling more consistent FLASH timing and dose-rate delivery.

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