bioRxiv · 11 Sept 2026 · Preprint · Open access

Distinct geometries, comparable interfaces: binding modes and thermodynamic implications in conventional and single domain antibodies

Hauser, Dangla-Pelissier + 1 more

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MARCH2/3 target FcγRI for K27-linked polyubiquitination and degradation to restrict the inflammatory response.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
MARCH2 and MARCH3 redundantly target FcγRI for K27-linked polyubiquitination and degradation, limiting inflammatory responses and disease severity.
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CAR-T cells and cancer nanovaccines: Comparative insights into advances and translational challenges.
Biotechnology advances · 1 Oct 2026 · Review
CAR-T cell therapies and cancer nanovaccines show promise but face distinct translational challenges, with recent advances highlighting their potential to reshape cancer treatment.
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https://jclub.com.au/a/42229669
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Metastasis enables immunogenicity through migrasome-mediated antigen release.
Nature Immunology · 1 Oct 2026 · Journal Article
Metastasis promotes tumor immunogenicity by producing migrasomes that deliver antigens and activate immune responses, reducing metastatic growth.
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