bioRxiv · 20 Sept 2026 · Preprint · Open access

Bivalent bispecific CD28 antibodies reinforce T-cell responsiveness and revert anergy/quiescence in patients treated with bispecific CD3 antibodies

Zekri, Koehler + 16 more

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CAR-T cells and cancer nanovaccines: Comparative insights into advances and translational challenges.
Biotechnology advances · 1 Oct 2026 · Review
CAR-T cell therapies and cancer nanovaccines show promise but face distinct translational challenges, with recent advances highlighting their potential to reshape cancer treatment.
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Metastasis enables immunogenicity through migrasome-mediated antigen release.
Nature Immunology · 1 Oct 2026 · Journal Article
Metastasis promotes tumor immunogenicity by producing migrasomes that deliver antigens and activate immune responses, reducing metastatic growth.
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Drug-controlled CAR T cells through the regulation of cell-cell interactions.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
Venetoclax-controlled DROP-CAR T cells effectively regulate tumor targeting and reduce off-tumor toxicity through dose-dependent cell-cell interaction modulation.
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https://jclub.com.au/a/41714721
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