RNAcomp2D: a web tool to execute multiple methods and visually compare predictions of RNA secondary structure

RNAcomp2D enables simultaneous comparison of multiple RNA secondary structure prediction methods through a unified web interface.

• Why it matters: Comparing predictions from different computational models is difficult due to varied interfaces and requirements, hindering comprehensive analysis of RNA structures.
• What they did: The tool accepts RNA sequences from users or RNAcentral, runs several thermodynamic and deep learning-based prediction methods packaged in containers, and displays all results together visually.
• The result: RNAcomp2D facilitates easy comparison of multiple predictions and reference structures in a single view, supporting scalability for future method additions and advancing RNA structural analysis.