Clusterin in disease pathology
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Mitochondrial fission factor phosphorylation at Ser155 drives ferroptosis by promoting organelle fragmentation and oxidative stress in cells.
HSPA6 promotes lenvatinib resistance in hepatocellular carcinoma by stabilizing TXNRD1 through phase separation, reducing ferroptosis, and correlating with poor patient outcomes.
TPI1 is overexpressed in head and neck squamous cell carcinoma and promotes tumor progression by conferring ferroptosis resistance, with high expression predicting poor survival.
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