Cardiovascular Disease and Adiposity
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Androgen-AR signaling suppresses mitochondrial respiration in visceral fat by downregulating Pdhb, contributing to sex differences in fat accumulation and metabolic risk.
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ENPP1 prevents extracellular cGAMP accumulation in brown adipose tissue, reducing insulin resistance and obesity in high-fat diet conditions.
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The 2026 ACC/AHA guideline provides comprehensive recommendations for managing dyslipidemia to reduce cardiovascular risk.
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