Viral-associated cancers and disorders
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Latest in Viral-associated cancers and disorders
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EBV-encoded v-snoRNA1 guides 2'-O-methylation of human rRNAs at conserved sites, reducing translation and slowing cell proliferation to regulate viral latency and lytic switch.
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High IGF2BP2 expression drives tumor growth and immune evasion in PTCL, with overexpression observed in 3 independent cohorts and 196 patient samples.
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Aminopeptidase N serves as a receptor for hedgehog merbecoviruses, with species-specific binding revealed by cryo-EM analysis.
- Open access
EBV transcriptional regulators extensively alter human gene expression, with over 100,000 binding events affecting nearly a quarter of human genes.
- Open access
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Lung transplant for lung-limited stage IV NSCLC resulted in 100% one-year survival in selected patients, significantly outperforming medical management alone.
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