Local acetyl-CoA production and acetate recycling regulate chromatin dynamics independently of overall metabolite levels, influencing gene expression and epigenetic states.
FEMS Yeast Research
Oxford University Press · Microbiology & Mycology · ISSN 1567-1356, 1567-1364
- Impact (2-yr)
- 4.4
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- Papers this month
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Latest in FEMS Yeast Res
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Direct RNA Sequencing refines the Saccharomyces cerevisiae transcriptome by adding UTRs to over 2,400 genes, improving boundary annotations by up to 28.9%.
Yeast-based chemical genetic approaches reveal molecular targets of 17 Pacific natural products, advancing understanding of their mechanisms of action.
Fungi on human skin utilize diverse, yet poorly understood, iron acquisition strategies crucial for survival in the iron-restricted cutaneous environment.
High- and very-high-gravity fermentation enhances substrate loading and product titers, with potential to improve efficiency and sustainability across bioproduct industries.
Kveik yeast strains exhibit heightened basal stress gene expression and maintain growth-related processes under heat and ethanol stress, enhancing their industrial resilience.
The Saccharomyces Genome Database has evolved over 30 years into a global hub for genetics, functional genomics, and human disease research, shaping eukaryotic biology.
Harnessing yeast biodiversity, including diverse natural and engineered strains, advances industrial bioproduction with over 100 strain libraries and extremophilic models.
- Open access
Genomic analysis reveals that wine yeasts, despite domestication bottlenecks, exhibit high genome dynamism and extensive variation, enabling adaptation and innovation.
RAIN enables multiplex genome engineering in Saccharomyces cerevisiae with up to five integrations without cloning expression cassettes, streamlining pathway optimization.
Nma1 modulates phosphate-sensing signaling in Saccharomyces cerevisiae independently of its NAD+ synthesis activity, reducing Pho4 nuclear localization during phosphate depletion.
Advances in sequencing and genomics have expanded Saccharomyces cerevisiae research from a single reference genome to thousands of diverse isolates, revealing extensive genetic variation.
Adaptive laboratory evolution enabled Irish S. eubayanus strains to metabolize maltose through MAL locus duplication and MalR mutations, with W307L mutation fully restoring maltose utilization.
Engineering a Kluyveromyces marxianus sugar transporter enabled co-consumption of glucose and xylose, reducing glucose affinity by 20-fold and increasing xylose affinity threefold.
Replicative age predicts metabolic decline in industrial yeasts, with viability dropping from 88% in young cells to 5% in oldest cells in S. pastorianus.
Complete yeast genome sequencing has transformed biology, enabling genome-scale design and synthetic genomics in Saccharomyces cerevisiae with over 6,000 genes.
- Open access
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Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
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- Lung Cancer Treatments and Mutations5
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- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4