Plant Physiol BiochemJClub
Comparative foliar elicitation with yeast extract and sodium butyrate reshapes terpenoid metabolism in Salviaofficinalis.
Plant Physiology and Biochemistry · · Journal Article · Open access
Ebadi, Abdollahzadeh + more
Abstract ↗AI summary
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Sodium butyrate foliar elicitation in Salvia officinalis reshapes terpenoid metabolism, driving >10-fold β-caryophyllene accumulation (31% of total extract) and 3.55-fold ferruginol enrichment.
- Why it matters: Cost-effective, scalable elicitation is needed to improve consistent production of high-value terpenoids in Salvia officinalis, while maintaining desirable chemotypes.
- What they did: Plants were treated with yeast extract (2 g L−1) or sodium butyrate (25 and 50 mM), then analyzed using integrated GC-MS metabolite profiling and qRT-PCR for pathway gene expression.
- The result: NaB produced a strong sesquiterpene synthase SoHUMS (>15-fold) transcriptional response and increased antiproliferative activity against MCF-7 cells, with docking/ADMET supporting ferruginol and other NaB-enriched terpenoids as contributors.
The findingWhy it mattersWhat they didThe result
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