A pangene family atlas of cereals uncovers hidden intraspecific and interspecific diversity.

A pangene-based, domain-defined framework across four major cereals uncovers nearly 500 pangene families with 59–264% higher membership than single-genome analyses.

• Why it matters: Orthogroups and single-genome views can miss allele- and locus-level diversity, leaving much of cereal pangenome variation uncharacterized.
• What they did: The study builds and analyzes nearly 500 pangene families using a pangene-based, domain-defined framework, including 320 rice genomes, and tracks family behavior across three complementary dimensions.
• The result: Many families show accumulation curves far from saturation and extensive remodeling of membership and copy-number allocation, enabling deeper characterization of hidden intraspecific and interspecific diversity.

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