HvMAPK5-Mediated Phosphorylation of HvWRKY75 Enhances Salt Tolerance in Barley.

HvMAPK5 phosphorylates HvWRKY75 at Ser21, boosting HvWRKY75 stability and transcriptional activation of HvHKT1;2, which enhances salt tolerance in barley.

• Why it matters: Soil salinization limits cereal yields, and the molecular links connecting kinase signaling to ion transporter regulation in barley under salt stress remain unclear.
• What they did: The study identified a regulatory module with HvHKT1;2, HvWRKY75, and HvMAPK5; HvHKT1;2 was tested by overexpression/knockdown, while HvMAPK5–HvWRKY75 interaction and Ser21 phosphorylation were assessed under salt stress.
• The result: HvMAPK5 overexpression increased HvWRKY75 protein abundance and HvHKT1;2 expression and improved salt tolerance, whereas HvMAPK5 knockdown promoted HvWRKY75 degradation and reduced salt tolerance.

AI summary of the abstract · may contain errors · not medical advice · read the paper.