Positive feedback between cytokinins and sugars controls correlative inhibition in two-branched pea seedlings.

Positive feedback between sugars and cytokinins in two-branched pea seedlings is linked to correlative inhibition, with Sug or CK deficiency increasing unequal-branched plants.

• Why it matters: Correlative inhibition coordinates shoot dominance within one plant, but the regulatory circuitry connecting sugar status and cytokinin signaling was unclear.
• What they did: The Sug–CK model was tested by inducing Sug deficiency (partial cotyledon removal) and CK deficiency (inhibiting CK synthesis), then measuring CK signaling via PsRR5 expression in apical buds.
• The result: Sug–CK positive feedback was supported because Sug deficiency lowered CK signal and CK synthesis inhibition reduced Sug accumulation; strigolactone signaling (rms5/rms1, rms4) and BRC1 were required for CI responses.

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