SynBioFooDB: a comprehensive resource for synthetic biology-driven food biomanufacturing.

SynBioFooDB integrates 74 237 standardized food-related compounds with curated biomanufacturing evidence for 1054 compounds and 2002 biosynthetic pathways for 971 compounds.

• Why it matters: Evidence linking food-related compounds to biosynthetic pathways and microbial biomanufacturing is fragmented and underrepresented, limiting cross-study comparison, evidence synthesis, and rational design.
• What they did: The knowledgebase compiles standardized chemical identities and annotations plus expert-curated records from 5592 publications, and includes 2002 literature-reported pathways and computationally predicted candidate pathways when absent.
• The result: It enables systematic exploration, comparison, and rational design of microbial production strategies by connecting compound context, quantitative production metrics, and pathway architectures.