ArthroVerse: mapping protein family diversity across arthropod-associated microbiomes.

ArthroVerse is the first comprehensive database of protein families derived from arthropod-associated metagenomes, integrating metagenomic and reference genome proteins for insect microbiomes.

• Why it matters: Metagenomic sequencing has expanded, but the functional and structural organization of proteins in arthropod-associated microbiomes remains largely unexplored.
• What they did: The team generated non-redundant protein families using rigorous filtering, deduplication, and clustering, then annotated them with microbial taxonomy, host associations, protein structural information, and carbohydrate-active enzyme predictions.
• The result: The integrated dataset enables systematic exploration of functional diversity, evolutionary relationships, and host-microbe interactions in insect-associated microbial communities, supporting microbial ecology and arthropod physiology research.