Cardiovascular Complications of Chronic Liver Disease.

Cardiovascular disease is a major contributor to morbidity and mortality in patients with chronic liver disease, especially in those with metabolic dysfunction-associated steatotic liver disease.

• Why it matters: Understanding the bidirectional interactions between the liver and cardiovascular system is crucial because cardiovascular risk is underrecognized in liver disease patients, impacting outcomes.
• What they did: The review summarizes mechanisms like inflammation and endothelial injury, discusses noninvasive liver fibrosis assessment, and evaluates cardiovascular risk through imaging and biomarkers in 158 patients.
• The result: Enhanced recognition and early detection of liver and cardiovascular disease can improve risk stratification and outcomes, with future research needed to develop liver-informed cardiovascular risk models.