Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans.
- Open access
Molecular pathways involving c-di-GMP regulators and biofilm components drive Mn(II) oxidation in Pseudomonas resinovorans MOB-513, with key genes identified.
- Why it matters: Understanding these pathways fills a critical knowledge gap in microbial manganese oxidation, which is important for bioremediation and environmental management of manganese pollution.
- What they did: Researchers used transposon mutagenesis and targeted gene analysis to identify mutants affecting Mn(II) oxidation, biofilm formation, and c-di-GMP levels, focusing on genes pilC, algR, hk05390, and dgc05792.
- The result: Findings reveal two c-di-GMP-dependent regulators modulate Mn(II) oxidation, providing new targets for enhancing biological manganese removal and advancing biotechnological applications.