medRxivJClub
Tuberculosis treatment outcome in Cameroon: a systematic review and meta-analysis
medRxiv · · Preprint · Open access
Cheuyem, Zefack + 5 more
Abstract ↗AI summary
The abstract is read at the publisher; the summary is JClub's.
Pooled TB treatment success in Cameroon was 78.2% (95% CI 73.8–82.1) across 71,784 participants, with very high between-study heterogeneity (I2=98.2%).
- Why it matters: National evidence on routine-care TB outcomes in Cameroon is limited, making it hard to quantify gaps and target interventions for unfavorable outcomes.
- What they did: A systematic review and random-effects meta-analysis of 32 observational studies (1998–2022) estimated pooled WHO-defined outcomes and adjusted odds ratios for predictors.
- The result: Mortality was 8.1% (95% CI 5.5–11.7) and loss to follow-up 6.8% (95% CI 5.0–9.1), with HIV positivity (AOR=2.57) and absence of antiretroviral therapy (AOR=1.71) linked to worse outcomes.
The findingWhy it mattersWhat they didThe result
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