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Human immunodeficiency virus and tuberculosis coinfection prevalence and treatment outcomes in Cameroon: a systematic review and meta-analysis
medRxiv · · Preprint · Open access
Cheuyem, Tchamani + 6 more
Abstract ↗AI summary
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Pooled HIV prevalence among tuberculosis patients in Cameroon is 29.2% (95% CI: 26.3–32.3) across 67 studies, with strong regional and clinical variation.
- Why it matters: Cameroon’s national burden of HIV/TB coinfection is unclear because evidence has not been synthesized across regions and populations, limiting planning for TB-HIV care.
- What they did: A PRISMA 2020 systematic review and meta-analysis (PROSPERO: CRD420261399169) pooled prevalence and treatment outcomes from 70 Cameroon studies (1995–2023) using random-effects models and assessed heterogeneity with I2.
- The result: Among coinfected patients, treatment success is 75.9% and mortality 21.1%, and lack of ART is linked to unfavorable outcomes (AOR = 1.90; 95% CI: 1.15–3.12).
The findingWhy it mattersWhat they didThe result
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