Longitudinal Participation and Cognitive Score Interpretation in the J-TRC Webstudy

In the Japanese Trial-Ready Cohort (J-TRC) Webstudy, only 19.4% and 14.1% of eligible participants contributed cognitive data at or beyond three and five years, respectively.

• Why it matters: Web-based cognitive registries enable remote follow-up, but participant-driven reassessment can limit long-term data yield and complicate interpretation of repeated scores.
• What they did: Using over six years of J-TRC Webstudy data (registrations through March 31, 2025; assessments through May 31, 2026), the study quantified participation patterns and modeled retest-dependent cognitive change.
• The result: After 365 days without assessment, the estimated probability of resuming within two years was 7.2%, and prior worse scores predicted lower subsequent assessment odds (CFI aOR 0.952; Cogstate aOR 0.845).

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