Neurons entrain and shape an intrinsic arteriole rhythm that distributes blood across the cortical mantle

Neuronal stimulation entrains an intrinsic arteriole vasomotion rhythm at fvaso ~ 0.1 Hz, and stimulation frequency governs how oscillatory blood distribution spreads across cortical territory.

• Why it matters: It remains unclear whether cortical vaso-oscillation patterns merely follow neural drive or instead reflect neuronal entrainment of a vascular oscillator that can shape functional blood flow maps.
• What they did: The study suppressed endothelial hyperpolarization to test whether resting oscillations persist, then measured vascular responses to neural activity across frequencies, including simultaneous driving of neighboring cortical areas.
• The result: Resting-state oscillations stayed intact but neural-evoked vascular responses weakened, neural activity near 0.1 Hz was resonantly amplified, and the area closer to fvaso captured more vascular territory.

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