bioRxivJClub
Extended Pavlovian conditioned approach training and devaluation in Long-Evans rats using time-restricted feeding
bioRxiv · · Preprint · Open access
Rainer, Brooks + 2 more
Abstract ↗AI summary
The abstract is read at the publisher; the summary is JClub's.
Extended Pavlovian conditioned approach training in male and female Long-Evans rats under time-restricted feeding increases the proportion of sign-trackers and preserves satiety sensitivity.
- Why it matters: Food deprivation used in PCA can elevate stress and potentially bias animals toward sign-tracking, while most analyses miss behaviors beyond lever pressing and food-cup entry.
- What they did: Rats received extended PCA training, then satiety-induced reward devaluation under time-restricted feeding; researchers expanded behavioral scoring beyond lever pressing and food-cup entry.
- The result: Under TRF, rats gained weight across PCA training and maintained caloric intake relative to ad libitum, and all rats showed sensitivity to satiety-induced reward devaluation regardless of sex or devaluation condition.
The findingWhy it mattersWhat they didThe result
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- Open access