Roost: Avian Influenza Host Genomics Resource

Roost compiles evidence for HPAI host susceptibility, linking 1,300+ publications and reports to 2,000+ avian genome assemblies, while noting 51% of detected species are missing.

• Why it matters: Evidence on which avian species are susceptible is fragmented across papers, surveillance, and genomic datasets, limiting comparisons of host biology and risk.
• What they did: The team built a web resource using large language model-assisted literature analysis plus comparative genomics to connect species, genes, and molecular mechanisms to their supporting evidence.
• The result: Roost centralizes documented disease evidence with genome analyses, highlighting sequencing and functional research priorities, especially for species with HPAI detections not represented in the corpus.

AI summary of the abstract · may contain errors · not medical advice · read the paper.