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Core schema instability in youth at clinical high risk for psychosis: within-person variability as an index of self-belief precision
medRxiv · · Preprint · Open access
Broekhuijse, Saxena + 13 more
Abstract ↗AI summary
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Core schemas in 411 youth at clinical high risk for psychosis show substantial within-person fluctuation, with within-person variance explaining 41.3%–50.6% of BCSS variance.
- Why it matters: If schemas are treated as stable traits, unmeasured fluctuations could mask belief changes that occur before psychosis emergence.
- What they did: Using NAPLS 2 longitudinal data, 411 CHR and 194 controls completed BCSS at least three times over 24 months; models estimated within-person SD differences, correcting for floor scores and mean level.
- The result: Latent within-person SD was higher in CHR on all four subscales, especially negative-self (ratio 1.71, 95% CrI [1.50, 1.94]), largely independent of shared improvement and psychotropic medication effects.
The findingWhy it mattersWhat they didThe result
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