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A cell-intrinsic steroidogenic checkpoint constrains female Th2 effector output independently of gonadal hormones

bioRxiv · 21 Sept 2026 · Preprint · Open access

Pramanik, Zhao + 3 more

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Development of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
HEP-50768, a potent and selective inverse agonist of MRGPRX4, suppresses bile-acid-induced pruritic behaviors in humanized rats, indicating its potential for cholestatic itch treatment.
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IL-17D reprograms CD93(+) antigen-presenting cells in the glioblastoma microenvironment.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
Restoring IL-17D in glioblastoma reprograms CD93(+) antigen-presenting cells, extending survival by activating immune responses in mouse models.
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Age-adjusted machine learning identifies facial skin microbes associated with skin quality among Korean women.
mSystems · 22 Sept 2026 · Journal Article
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