Retinoids in leukemia and cellular processes
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FAD acts as a natural suppressor of cytosolic DNA and RNA sensors, reducing immune activation and inflammation, with levels dropping during viral infections to enhance immunity.
ELN-DAVID issues key laboratory and clinical guidelines for FLT3-ITD MRD testing in AML patients in remission, supporting its role in current care standards.
Dietary vitamin A limits intestinal tuft cell differentiation via epithelial retinoic acid signaling, reducing tuft cell numbers and influencing immune responses in mice.
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The gut microbiota directs a three-day pathway of vitamin A derivatives from epithelial cells to T cells, shaping intestinal adaptive immunity.
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