A two-step machine learning approach enables transferable prediction of small-molecule retention times across different chromatographic conditions, outperforming existing methods.
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Protein purification and stability
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Multi-cycle reagent recycling in in vitro transcription and purification reduces raw-material costs by over twofold while maintaining RNA quality over five cycles.
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Engineering vector plasmids and cell lines has significantly enhanced rAAV production, overcoming capacity bottlenecks in the HEK293 system to meet clinical demand.
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