GutBiomeDB: an integrated human gut microbiome database of 168 464 samples.

GutBiomeDB integrates uniformly processed human gut microbiome data from 168 464 samples across 482 BioProjects, covering 72 countries, 224 disease conditions, and seven life stages.

• Why it matters: A unified, well-curated gut microbiome database with consistent processing and multiple analysis tools is still missing despite expanding public datasets.
• What they did: The platform reuses Abdill et al.’s taxonomic profiles to build a matrix spanning 4680 taxa and 3142 genera, with manually curated metadata and four analysis tools.
• The result: GutBiomeDB enables differential comparisons with random-effects meta-analysis, co-occurrence network comparisons, life-stage genus trajectories, and Health Index similarity scoring for uploaded profiles.

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