YEASTRACT+: the 2026 update with focus on global quantitative transcription regulation data and metabolic engineering applications.

YEASTRACT+ now provides quantitative transcription regulatory associations between transcription factors and target genes across 13 yeast species, enabling TF impact ranking and metabolic engineering integration.

• Why it matters: Prior yeast regulatory resources lacked quantitative measures linking TFs to gene expression levels, limiting predictive analysis and downstream modeling for fundamental and applied uses.
• What they did: The 2026 update integrates YEASTRACT, PathoYeastract, and NCYeastract and upgrades regulatory associations with quantitative impact; it adds tools for quantitative TF rank prediction and for incorporating TF effects into genome-scale metabolic models.
• The result: The release extends curated quantitative access to transcription control in 13 yeast species, including Cryptococcus neoformans and Rhodotorula toruloides, supporting exploitation for biological, biotechnological, and health-related applications.

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