OAS-nano: the Observed VHH Space Database.

OAS-nano is the first large-scale, web-accessible database containing over 73 million unique VHH sequences from camelid species.

• Why it matters: This addresses the lack of comprehensive, publicly available VHH sequence resources, which are crucial for advancing therapeutic, diagnostic, and research applications.
• What they did: The database was created by processing 16 public and 1 unpublished repertoire sequencing datasets using a standardized pipeline to extract high-quality VHH sequences, with metadata and annotations included.
• The result: OAS-nano enables users to identify sequences suitable for their specific use cases, facilitating research and development in VHH-based technologies.