bioRxiv · 18 Aug 2026 · Preprint · Open access

A bivalent lysine-acetylated small-molecule binding site in MYC

Gupta, Truica + 20 more

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Five-year survival with neoadjuvant therapy in melanoma: updated pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC).
Nature Medicine · 1 Oct 2026 · Journal Article
Five-year survival rates with neoadjuvant immune checkpoint inhibitors reach up to 87.5% in melanoma, significantly outperforming targeted therapies and combination regimens.
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A Foundation Model of Cancer Genotype Enables Precise Predictions of Therapeutic Response.
Cancer Discovery · 1 Oct 2026 · Journal Article
MutationProjector, a cancer genotype foundation model, accurately predicts therapeutic resistance and sensitivity across multiple cancer types, surpassing existing methods in all tested contexts.
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Mechanistic modeling reveals a configurable AP-1 network governing cell-state heterogeneity and adaptive plasticity in melanoma cells.
Cell Reports · 22 Sept 2026 · Journal Article
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