Diet, Metabolism, and Disease
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A very-low-carbohydrate diet yields 2-3 times greater improvements in hepatic insulin sensitivity than Mediterranean or very-low-fat diets during 10% weight loss in metabolically unhealthy obesity.
ALG-055009 significantly reduces liver fat in non-cirrhotic adults with MASH, with up to 33.2% relative decrease at higher doses in a phase 2a trial.
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High intake of sugar-sweetened beverages and fruit juice during childhood significantly increases the risk of developing hypertension by adulthood, with reductions seen when replacing these with whole fruits, milk, or water.
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