ImmunEscpMap: a gene-centered knowledgebase for immune escape in cancer and viral infection.

ImmunEscpMap catalogs 55,711 gene-evidence records linking immune escape mechanisms in cancer and viral infection, involving 667 genes across diverse evidence types.

• Why it matters: Understanding immune escape is crucial for developing targeted therapies, but current data are fragmented across multiple sources, complicating gene prioritization and mechanistic insights.
• What they did: The authors built ImmunEscpMap, a gene-centered knowledgebase that integrates evidence from PubMed and GEO, organizing data into immune-escape mechanisms and viral contexts, with detailed multi-omics and clinical information.
• The result: ImmunEscpMap enables researchers to prioritize candidate genes and explore immune escape processes through a user-friendly web interface, supporting follow-up experiments and cross-domain analysis.