Regulatory plasticity of the 26S proteasome in plants.

The plant 26S proteasome exhibits dynamic regulatory plasticity, with its abundance, composition, activity, and localization continuously reconfigured across multiple pathways.

• Why it matters: Understanding this plasticity is crucial because it positions the proteasome as a central hub in plant regulatory networks, influencing responses to stress and development.
• What they did: The review synthesizes recent advances in immunity, stress, hormone signaling, organelle communication, and autophagy, highlighting the proteasome's non-proteolytic functions and its flexible regulation.
• The result: This perspective suggests that manipulating proteasome distribution and assembly could inform strategies to enhance crop resilience by optimizing proteolytic capacity.